Scholastica was a sixth-century Italian religious and the sister of St. Benedict. Most of what is known of her comes from the Dialogues of Pope St. Gregory the Great, where she is also presented as Benedict's twin.

Tradition says she consecrated herself to God from childhood and lived with other religious women near Monte Cassino. According to the story, brother and sister met once a year for spiritual conversation. At their last meeting she asked him to stay longer, and when she prayed, a storm broke out so that Benedict could not leave. She is said to have died three days later, around 543.